16-strain probiotic combination

• Provides 15 billion CFU per dose
• 16 probiotic strains providing comprehensive support for intestinal health
• Long-term maintenance probiotic for the temporary modification of gut flora
• No refrigeration necessary
• Potency guaranteed through expiration

HMF^® Multi Strain is a comprehensive combination of 16 probiotic strains to support a healthy normal digestive flora. Each shelf-stable capsule provides a variety of lactic acid bacteria (LAB) strains to support a favourable gut microflora in both the small and large intestines.¹ HN019, a probiotic strain included in this formula, was shown in a placebo-controlled trial to promote a healthy gut flora.² It significantly increased Bifidobacteria and Lactobacilli counts, while reducing the population of Enterobacteria (a genus that includes many pathogenic bacteria).² Similarly, Genestra’s HMF probiotic consortium, Lactobacillus acidophilus (CUL-60 and CUL-21), Bifidobacterium bifidum (CUL-20) and Bifidobacterium animalis subsp. lactis (CUL-34), contained in HMF^® Multi Strain has been demonstrated in clinical trials to support intestinal comfort and promote a healthy microflora balance in the gastrointestinal tract.^3-5 This convenient shelf-stable format has potency guaranteed through expiration and may improve patient compliance.

REFERENCES:

1. Govender M, Choonara YE, Kumar P, du Toit LC, van Vuuren S, Pillay V. AAPS PharmSciTech. 2014 Feb;15(1):29-43.
2. Ahmed M, Prasad J, Gill H, Stevenson L, Gopal P. Impact of consumption of different levels of Bifidobacterium lactis HN019 on the intestinal microflora of elderly human subjects. J Nutr Health Aging. 2007 Jan-Feb;11(1):26-31.
3. Williams EA, Stimpson J, Wang D, Plummer S, Garaiova I, Barker ME, et al. Aliment Pharmacol Ther. 2009 Jan;29(1):97-103.
4. Madden JA, Plummer SF, Tang J, Garaiova I, Plummer NT, Herbison M, et al. Int Immunopharmacol. 2005 Jun;5(6):1091-7.
5. Plummer SF, Garaiova I, Sarvotham T, Cottrell SL, Le Scouiller S, Weaver MA, et al. Int J Antimicrob Agents. 2005 Jul;26(1):69-74.

EACH CAPSULE CONTAINS:
Probiotic Consortium ………………………………….. .15 billion CFU
Lactobacillus acidophilus (CUL-60 & CUL-21) ………. .10 billion CFU
Bifidobacterium animalis subsp. lactis (CUL-34) & Bifidobacterium bifidum (CUL-20) …………………….. . 2.5 billion CFU
Lactobacillus salivarius (CUL-61)…………………………. . 0.3 billion CFU
Lactobacillus fermentum (CUL-67) ……………………….. . 0.2 billion CFU
Lactobacillus gasseri (CUL-09) ………………………….. . 0.2 billion CFU
Lactobacillus acidophilus (NCFM®) ……………………….. . 0.2 billion CFU
Lactobacillus casei (CUL-06) ……………………………. . 0.2 billion CFU
Lactobacillus paracasei (CUL-08) ………………………… . 0.2 billion CFU
Bifidobacterium animalis subsp. lactis (CUL-62)……………… . 0.2 billion CFU
Bifidobacterium breve (Bb-18) …………………………. . 0.2 billion CFU
Bifidobacterium animalis subsp. lactis (HN019) ……………… . 0.2 billion CFU
Lactobacillus plantarum (CUL-66)………………………… . 0.2 billion CFU
Streptococcus salivarius subsp. thermophilus (CUL-68) ……….. . 0.2 billion CFU
Lactobacillus rhamnosus (HN001)………………………… . 0.2 billion CFU

Non-Medicinal Ingredients: Cellulose, hypromellose,sunower lecithin,silica.

Ingredients used to maintain viability of probiotics (dipotassium phosphate, monopotassium phosphate, trehalose, sucrose, sodium chloride, sodium ascorbate, magnesium sulfate, maltodextrin,monosodium L-aspartate).