PHARMAGABA

$54.50

Available on backorder

PharmaGABA™ is naturally-sourced, bioidentical GABA, one of the body’s main calming neurotransmitters, manufactured through a natural fermentation process which has been shown to result in a more clinically effective GABA than generic synthetic forms. This product temporarily promotes relaxation.

60 tabs

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Product Description

PHARMAGABA

PharmaGABA™ is naturally-sourced, bioidentical GABA, one of the body’s main calming neurotransmitters, manufactured through a natural fermentation process which has been shown to result in a more clinically effective GABA than generic synthetic forms. This product temporarily promotes relaxation.

What is GABA?

GABA (gamma-aminobutyric acid) is a naturally occurring amino acid in the brain and is a major inhibito- ry neurotransmitter in the central nervous system (CNS). Being an inhibitory neurotransmitter, GABA blocks nerve impulses, slowing down the activity of nerve cells and preventing them from over-firing. Frequent over-firing of brain cells can lead to cell death, meaning that stress can actually kill brain cells. Keeping GABA levels optimal can help prevent this. Thus, GABA serves as a critical calming agent for the body, helping to combat stress and anxiety.

The brain synthesizes GABA from glutamate, an excitatory neurotransmitter. These two neurotransmitters work together in a beautifully orchestrated system of checks and balances. Neurotransmitters are the brain’s basic components of communication, and when there is a breakdown in this communication system, brain function becomes affected. In stressful situations, GABA levels in the body can decrease, and this delicate system becomes out of balance. In a study on humans, prefrontal brain GABA levels decreased by 18% after acute psychological stress, specifically threat of shock (Hasler, G, et al, Am J Psy- chiatry, 2010). Thus, supplementation with PharmaGABATM, a natural, bioidentical GABA, may be of bene- fit in helping to cope with stressful situations, whether they arise from daily or extreme stress.

PharmaGABATM for Academics & Athletics

Because of GABA’s effect on the parasympathetic nervous system, and its ability to help to increase the production of alpha brain waves, supplementation of PharmaGABATM may be of great benefit in situations where a relaxed state of mind is necessary. If the mind is relaxed, it allows for clear thinking, better focus, and greater concentration. In this respect, GABA has been found to be of benefit in academics, in helping to improve learning capacity.

PharmaGABATM was given to elementary school students in Japan, to examine GABA’s relaxing effect and its potential to improve students’ learning efficiency. Results showed that GABA suppressed the secretion of CgA (salivary chromogranin A; secreted in times of psychological stress), demonstrating reduced stress at the time of learning. An increased accuracy rate of testing was also observed, as well as a signifi- cant reduction in tension toward learning (as measured by a Manifest Anxiety Scale).

Researchers concluded that PharmaGABATM was effective in improving students’ learning efficiency and in helping to improve students’ test results (Unpublished data provided by Pharma Foods International Co. Ltd.).

This concept also holds true with respect to athletes and sports performance. Athletes often refer to this state of mind as being “in the zone,” where their ability to relax and focus leads to a greater level of con- centration on their performance and a reduction in pre-competition nervousness.

Immune Function

Stress and anxiety impact the immune response and are associated with immunosuppression. GABA has been shown to play a role in enhancing immune function in stressful situations. In one particular study, eight acrophobic subjects (those with a fear of height) were asked to cross a suspended bridge, a truly stressful situation for them. Salivary IgA was monitored during the crossing of the bridge. Stress lowers salivary IgA, while relaxation raises this marker. The placebo group showed marked decrease of their IgA levels, while those given GABA showed significantly higher IgA levels (Adham M, et al, Biofactors, 2006).

Sleep

Another benefit of GABA’s ability to promote relaxation is that it may be helpful in inducing sleep. Certain GABA receptors are highly expressed in the thalamus, the part of the brain that is distinctively important in the control of sleep and wakefulness. GABAergic inhibition in the thalamus is known to play a principal role in the generation of sleep brain waves. Thus, PharmaGABATM is suitable to take before bedtime to help promote a good night’s sleep and may be ideal for stress-induced insomnia.

Who Should Not Take: This product is not recommended for pregnant or lactating women, as well as young children, unless under the guidance of a health care practitioner. Use of PharmaGABATM may con- flict with taking anxiety medications. Most prescription drugs for anxiety work on the GABAergic system since this is known to play an important role in the pathophysiology of anxiety disorders. Do not take PharmaGABATM with excess alcohol consumption as it may exacerbate the relaxation effect of alcohol drastically.

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