Ortho Molecular Products Collagen Factors

Collagen Factors provides targeted precursors and cofactors known to be involved in the biochemical processes that help support healthy connective tissue formation, cartilage and joints. This formulation contains a patented ingredient with a high concentration of hyaluronic acid, free-form amino acids, key minerals and vitamin C.

Hyaluronic Acid Extract

Mobilee® is a patented , high-molecular-weight hyaluronic acid (HA), which supports the viscoelastic, lubricating properties of synovial fluid. In addition, it contains collagen and other glycosaminoglycans (GAGs) to help support skin and joint health. Hyaluronic acid also plays a role in the biophysical, biochemical and cell regulation processes in joint synovial tissues. Scientific evidence shows that Mobilee® supports chondrocytes and synovial cells function, and is two to four times more active than fermented sources of HA in nourishing and supporting the health of synovial fluid.1,2 The latest clinical research includes HA in proactive and maintenance approaches to joint care that helps to improve knee movement with mild knee joint discomfort in healthy people.

Specific Precursors

Collagen is comprised of and formed from the amino acids proline and lysine. Lysine is an essential amino acid the body relies on adequate dietary intake for its involvement in the synthesis of connective tissues. Proline is well-known for its involvement in the triple helix of collagen—it is regularly spaced with glycine in the amino acid sequence of collagen

fiber, which together comprise about 50% of total collagen sequencing. Proline is a source of an amino acid involved in muscle protein synthesis. Lysine helps support the linking and stabilization of collagen, and contributes to the collagen matrix formation of veins, arteries and capillaries. During procollagen synthesis, both proline and lysine are hydroxylated to hydroxyproline and hydroxylysine, a reaction requiring vitamin C as a cofactor.3-5 Inadequate levels of vitamin C can impact this reaction, resulting in incomplete formation of the helical structure, in which leads to a delicate and easily destroyed structure. Vitamin C is combined with two amino acids—lysine and proline—to form procollagen. Procollagen is then used to manufacture one of several types of collagen found in different tissues throughout the body.6-7

Targeted Cofactors

Zinc is an essential trace mineral that supports immune function. Requirements are highest when the body’s repair system is most active.

Manganese helps in the development and maintenance of bones. Nutritional co-factors that help support collagen formation include zinc, vitamin C and amino acids.