DFH Liposomal Vitamin C provides this key foundational nutrient formulated with
liposomal technology for optimal absorption and bioavailability. Each 5 ml serving (approximate-
ly 1 teaspoon) of this lemon flavoured formula provides 1000 mg vitamin C, as sodium ascorbate.
The sodium facilitates absorption of vitamin C via sodium-dependent transporters.
Immune system support immediately comes to mind when we think of vitamin C, but this nutrient
has a host of roles in various tissues and systems beyond bolstering immune defenses. As a
cofactor for enzymes involved in the synthesis of serotonin and norepinephrine, adequate vita-
min C levels may help individuals maintain a positive mental outlook and mount a healthy
response to everyday stress. Its function in catecholamine synthesis may be why vitamin C has
long been recognized as helping to support the adrenal glands. In fact, the adrenal glands contain
one of the highest concentrations of vitamin C in the body (in both the cortex and medulla),
underscoring that this nutrient is instrumental for far more than antioxidant effects.1
Vitamin C is required for function of the enzymes that transform the amino acids proline and
lysine into hydroxyproline and hydroxylysine, key components for synthesis of collagen—includ-
ing that which constitutes blood vessels—which underlies, in part, the crucial role of vitamin C in
cardiovascular health, and explains why easy bruising and bleeding are signs of vitamin C defi-
Vitamin C has long been considered as a requirement for biosynthesis of carnitine (from the
amino acid lysine), which is needed for enzymatic transport of fatty acids into the mitochondria
for subsequent oxidation and generation of ATP.2,3 This has been called into question,4 but nev-
ertheless, while a multitude of factors affect metabolism and body weight, marginal vitamin C
status may impair fat oxidation during submaximal exercise, and optimizing vitamin C levels may
facilitate fat loss.5,6
Finally, vitamin C’s antioxidant function is a hallmark of this nutrient. Vitamin C is a potent neutral-
izer of free radicals and helps to recycle vitamin E and glutathione. Increased levels of oxidative
stress are associated with a wide array of chronic health issues. They are both a potential contrib-
utor to, and a downstream effect of conditions including but not limited to type 2 diabetes,7 Alz-
heimer’s disease,8 other neurodegenerative disorders,9 and frailty in aging individuals.10,11
Many nutritionists argue the body’s need for vitamin C far surpasses the paltry RDA recommen-
dations. Dr. Linus Pauling, who pioneered extensive research on vitamin C, believed optima amounts exceed 2,000 mg daily, with even higher amounts potentially exerting a therapeutic effect in acute situations.
Certain circumstances may necessitate a high dose of vitamin C, but
high doses administered orally often lead to diarrhea and other forms
of GI discomfort, thus limiting the dose that can be given at one time.
Intravenous vitamin C is an effective alternative, but this option may be
logistically inconvenient and financially impractical for some individu-
als. Liposomal Vitamin C is an excellent solution to all of these obsta-
cles. Liposomal delivery provides a well-tolerated, easily absorbed and
highly bioavailable form of vitamin C without the unpleasant side-ef-
fects of high oral doses. Liposomal Vitamin C also offsets the decrease in absorption known to
occur with increasing oral doses.
In addition to enhanced absorption, nutrients delivered via liposomes enter the lymphatic circula-
tion first, bypassing first-pass metabolism in the liver, thus increasing bioavailability.12 Because
this product provides vitamin C as sodium ascorbate, individuals with gastrointestinal sensitivity
may tolerate this buffered form better than regular ascorbic acid.
WHAT ARE LIPOSOMES?
Liposomes are spheres made of phospholipids—the primary building blocks of cell membranes.
Owing to this structure, liposomes bond easily with cell membranes to facilitate intracellular
delivery of their nutrient cargo. Thanks to this enhanced delivery and absorption, nutrients deliv-
ered in liposomal form at lower doses may have equal or greater efficacy than higher doses pro-
vided in forms that are less bioavailable.
DFH Liposomal Vitamin C employs liposome particles that are 50-100nm in size,
in contrast to 200-600nm particles that are more commonly available from other manufacturers.
The smaller sized particles result in increased oral and cellular uptake and faster transmucosal
absorption in the mouth. In fact, it is recommended to hold the product in the mouth for 30 sec-
onds before swallowing to take advantage of this effective route of absorption. Additionally,
clearance of these particles from the bloodstream (via the liver and spleen) is inversely related to
size: the smallest particles circulate the longest, increasing the likelihood of absorption at their
target tissues. Note that the phospholipids used in this product are derived from sunflower leci-
thin (soy-free, non-GMO material).
BENEFITS OF LIPOSOMAL DELIVERY
• Superior absorption and intracellular delivery of nutrients
• Phospholipid structure allows for effective delivery of compounds with different solubilities
carried within the same particle (e.g., water- and lipid-soluble compounds)
• Liposomes penetrate the blood-brain barrier, an obstacle for other various formulations
• While there is an opportunity for quick absorption in the mouth, liposomes also survive the
acidic environment of the stomach, ensuring intestinal uptake and delivery to the lymphatic
• Liquid liposomal formulations are convenient for those who prefer to swallow fewer pills; also